Look Ma! No Hands!
All of the more radically inhuman Transfiguration charms deprive a Colossus of his hands and arms, with obvious consequences for the character’s ability to wield weapons and use hand-held tools. There are several options available for such Exalts to rearm themselves:
The Cannonade Turret Assembly and Weapon Turret Systems submodules both allow an Alchemical to wield weapons without hands, and Paramagnetic Tether Beam can also be employed to wield weapons or use tools. Characters could also use Manifold Transhuman Implants to acquire the Multiple Limbs mutation in the form of mechanical grappler arms or similar appendages – extra arms are extra, after all, even if you start with none.